This question is best deferred to appropriate caregivers. Side effects could be numerous and relatively common because three different drugs are being administered at the same time. Most of the side effects, however are minor and will be tolerated as patients continue to take the drugs. In rare instances, the side effects could be severe and life threatening requiring medication adjustment or complete discontinuation and change to completely different drug regimen. It is, therefore, highly advisable that patients return to their providers for scheduled visit and close follow up.